PHP13: INDICES FOR EVALUATION OF DRUG COST/UTILIZATION: EVERY SILVER LINING HAS A GRAY CLOUD

Every silver lining has a cloud.

Every cloud has a silver lining.

phamide, and Rituximab Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia] study).8 If the results of this pivotal trial confirm the findings of Byrd et al,7 it will have an important influence on the treatment strategy of patients with CLL. In recent years, 4 drug combination therapies with FCR and alemtuzumab or FCR and mitoxantrone in refractory/relapsed CLL patients wer...

Totally drug-resistant tuberculosis (TDR-TB) in India: every dark cloud has a silver lining.

In the early weeks of January 2012, a report of four cases of tuberculosis from Mumbai, India, stirred up a storm. India bears a giant’s share of the world’s multidrug-resistant tuberculosis (MDR-TB) burden, but these cases were different even though they came from a centre (Hinduja Hospital and Research Center) which has been reporting on the alarming escalation in drug-resistant TB in Mumbai ...

Every cloud has a silver lining: interpersonal and individual differences determinants of anger-related behaviors.

Two studies examined the effect of status and liking of the anger target on anger behavior and individual differences in anger-related behavior. Participants recalled anger instances in which the anger target was of higher/equal/lower status and/or liked/ unfamiliar/disliked; subsequently, they indicated which behaviors they had displayed. In both studies, anger behaviors could be grouped into ...

Regeneration: Every Clot Has a Thrombin Lining

Why do some amphibian organs regenerate and others do not? And why do most mammalian organs not regenerate? New work on lens regeneration indicates that the answer lies in the need for cells to dedifferentiate first, and that what makes them dedifferentiate may be the presence of thrombin in combination with cellular clotting factors.